AMBROSIO LAB

Engineering biomimetic skeletal muscle systems that can model age-related muscle functional declines provides promising opportunities for understanding muscle aging and drug testing. In this project…

AMBROSIO LAB

As of 2020, an estimated 654.1 million adults live with knee osteoarthritis (KOA) worldwide. Notably, women who are post-menopausal have higher incidence and severity of KOA compared to men. Despite this…

AMBROSIO LAB

Resident muscle stem cells (MuSCs) are essential for the regeneration of muscle. However, over time, there is a gradual depletion of the MuSC pool. While aged MuSCs display cell-autonomous deficits that contribute to…